A　facile　reflux　method　was　developed　to　prepare　Cu-doped　α-FeOOH　(α-(Fe,Cu)OOH)　nanoflowers　consisted　of　nanorods　with　a　length　of　200-400　nm　in　large　scale.　The　obtained　α-(Fe,Cu)OOH　samples　were　characterized　by　X-ray　diffraction,　scanning　electron　microscopy,　X-ray　photoelectron　spectroscopy　and　UV-vis　absorption　spectra,　and　their　catalytic　performances　were　evaluated　by　the　degradation　of　diclofenac　sodium　(DCF)　in　water　under　visible-light　irradiation　(λ　＞　420　nm)　in　the　presence　of　H2O2.　The　amount　of　doped　Cu,　reaction　time,　initial　pH,　catalyst　dosages　and　H2O2　dosages　were　investigated　for　their　effects　on　the　degradation　efficiency　of　DCF,　respectively.　The　results　demonstrated　that　α-(Fe,Cu)OOH　nanoflowers　exhibited　better　catalytic　performance　in　comparison　with　pure　α-FeOOH,　and　the　sample　doped　with　3%　Cu　(molar　ratio　of　Cu　to　Fe)　displayed　the　optimal　visible-light　photocatalytic　activity.　In　addition,　the　degradation　efficiency　of　DCF　increased　with　the　increasing　of　catalysts　and　H2O2　dosages,　but　decreased　with　the　elevating　of　initial　pH　in　the　range　of　5-8.　The　α-(Fe,Cu)OOH　nanoflowers　presented　excellent　stability　with　high　degradation　efficiency　even　after　five　cycles.　The　high　catalytic　activity　of　α-(Fe,Cu)OOH　might　be　attributed　to　a　special　two-way　Fenton-like,　photo-catalytic　mechanism　and　the　synergistic　activation　of　Fe　and　Cu　in　α-(Fe,Cu)OOH　towards　to　H2O2.　©　2016　Elsevier　B.V.