In　this　study,　a　comblike　amphiphilic　graft　copolymer　containing　poly(vinyl　chloride)　(PVC)　backbones　and　poly(oxyethylene　methacrylate)　[poly(ethylene　glycol)　methylether　methacrylate　(PEGMA)]　side　chains　was　facilely　synthesized　via　an　atom　transfer　radical　polymerization　method.　Secondary　chlorines　in　PVC　were　used　as　initial　sites　to　graft　a　poly[poly(ethylene　glycol)　methylether　methacrylate]　[P(PEGMA)]　brush.　The　synthesized　PVC-g-P(PEGMA)　graft　copolymer　served　as　an　efficient　additive　for　the　hydrophilicity　modification　of　the　poly(vinylidene　fluoride)　(PVDF)　membrane　via　a　nonsolvent-induced　phase-inversion　technique.　A　larger　pore　size,　higher　porosity,　and　better　connectivity　were　obtained　for　the　modified　PVDF　membrane;　this　facilitated　the　permeability　compared　to　the　corresponding　virgin　PVDF　membrane.　In　addition,　the　modified　PVDF　membrane　showed　a　distinctively　enhanced　hydrophilicity　and　antifouling　resistance,　as　suggested　by　the　contact　angle　measurement　and　flux　of　bovine　serum　albumin　solution　tests,　respectively.　Accordingly,　the　PVC-g-P(PEGMA)　graft　copolymer　was　demonstrated　as　a　successful　additive　for　the　hydrophilicity　modification,　and　this　study　will　likely　open　up　new　possibilities　for　the　development　of　efficient　amphiphilic　PVC-based　copolymers　for　the　excellent　hydrophilicity　modification　of　PVDF　membranes.　Copyright　©　2013　Wiley　Periodicals,　Inc.