＇The　template　approach＇　was　used　for　the　synthesis　of　eight　metal　phthalocyanine　complexes　containing　piperidine　group　(PEO)4PcM,　where　M　=　Zn,　Ni,　Co,　Cu,　PEO　=　2-(piperidin-l-yl)　ethyoxyl.　These　complexes　were　characterized　by　FTIR,　mass　spectrum,　elemental　analysis　and　so　on.　The　UV-Vis　absorption　spectra,　fluorescence　emission　spectra　and　capacity　of　photo-generating　singlet　oxygen　were　examined.　The　results　showed　that　two　zinc　phthalocyanine　complexes　possessed　high　molar　extinction　coefficient,　fluorescence　quantum　yield,　high　rate　of　photo-generating　singlet　oxygen.　The　complex　with　formula　β-(PEO)4PcZn　had　a　photoinhibition　effect　to　BEL7402　liver　cancer　cells　up　to　83%　in　case　that　the　irradiation　with　670　nm　laser　light　(dosage　1.2　J)　and　the　concentration　of　β-(PEO)4PcZn　with　10μmol/L　were　used.