Endotoxin　is　composed　of　lipopolysaccharid,　which　is　the　outer　cell-wall　component　of　Gram-negative　bacterials.　Endotoxin　leads　organism　to　fever,　in　serious　case　it　leads　up　the　patient　to　shock.　Endotoxin　is　very　stable　to　heat　or　organic　solvents,　the　usual　sterile　operation　is　difficult　to　remove　endotoxin.　The　result　of　the　research　shows　that　HBS　lignin　and　its　derivatives,　which　were　separated　from　plant　raw　materials　by　using　high　boiling　alcohol　as　a　solvent.,　can　adsorb　endotoxin.　At　room　temperature,　the　adsorbed　endotoxin　was　released　when　organic　solvent　was　added　to　the　system.　Separated　HBS　lignin　derivatives　from　lignin-endotoxin　complex　can　adsorb　endotoxin　again.　HBS　lignin　derivatives　are　new　functional　material　for　removing　endotoxin　in　medical　industry.