A　new　silicon　phthalocyanine　axially　substituted　by　Nipagin,　i.e.　bis　(4-methoxycarboxyl　phenoxy)　phthalocyaninatosilicon,　has　been　synthesized　and　characterized　by　IR,　NMR,　HPLC　and　elemental　analysis.　Its　electronic　absorption　spectra　and　fluorescence　spectra　in　different　solvents　were　investigated.　It　was　found　that　the　compound　existed　in　the　form　of　monomer　in　a　saline　solution　containing　2%　(φ)　Cremophor　EL　and　20%　(φ)　propanediol.　The　electronic　absorption　spectra　of　the　compound　in　the　above　saline　solution　were　typical　for　non-aggregated　phthalocyanines,　showing　an　intense　and　sharp　Q　band　at　683　nm　with　a　molar　absorption　coefficient　of　7.47　×　104　mol-1·L·cm-1.　The　compound　exhibited　a　relatively　strong　fluorescence　emission　at　690　nm　with　a　quantum　yield　of　0.34　and　with　a　fluorescence　lifetime　of　4.7　ns.　The　primary　in　vitro　assay　showed　the　compound　had　photodynamic　killing　activities　against　B16　melanoma　cells　with　a　LD50　(half　lethal　dose)　of　1.2　×　10-4　mol·L-1.