The　calcium　lignosulphonate　was　adopted　as　the　raw　material　to　prepare　the　amphoteric　lignin-based　flocculant,　denoted　as　LSDC.　Then　the　LSDC　was　adopted　to　flocculate　the　different　simulating　dye　effluents,　e.g.,　reactive　blue　X-BR,　reactive　yellow　X-R,　reactive　violet　K-3R　and　reactive　black　K-BR.　And,　different　flocculation　effectors　were　optimized.　It　can　be　concluded　that　the　flocculation　efficiency　of　LS　DC　has　found　to　be　effluent　pH　and　flocculant　dose　dependent.　The　discoloring　rate　increases　with　an　increase　in　the　LSDC　dose　ranging　from　0　to　150　mg/L.　However,　CODCr　of　the　simulating　dye　effluents　also　increases　by　addition　of　the　LSDC.　Consequently,　the　LSDC　should　be　limited　to　a　permissible　dose.　The　LSDC　contains　the　anionic　sulfonic　group　and　cationic　quaternary　ammonium　group.　Consequently,　the　kinds　and　number　of　the　function　groups　on　the　dye　molecular　chains　also　showed　great　effect　on　the　discoloring　efficiency.　For　the　reactive　dyes,　the　discoloring　flocculation　capacities　decreased　with　an　increase　of　the　numbers　of　the　functional　groups　of　the　dyes.　Among　the　effluent　pH　ranging　from　4　to　8,　the　discoloring　rates　of　the　reactive　blue　X-BR,　reactive　yellow　X-R,　reactive　violet　K-3R　and　reactive　black　K-BR　could　reach　83.78%,　99.39%,　98.25%　and　82.13%,　respectively.