A　high　performance　liquid　chromatographic　(HPLC)　method　has　been　developed　for　the　determination　of　quinoxyfen　residue　in　various　food　matrixes　including　soybean,　cauliflower,　cherry,　mushroom,　wine,　tea,　honey,　pork　liver,　chicken　and　eel.　The　analyte　was　extracted　by　ethyl　acetate,　and　then　purified　with　aminopropyl　solid　phase　extraction　(NH2　SPE)　cartridge.　Post-extraction　gel　permeation　chromatography　(GPC)　was　used　for　animal　(except　honey)　and　fishery　products　prior　to　NH2　SPE　cleanup.　The　average　recoveries　and　relative　standard　deviations　(RSDs)　for　the　analysis　of　all　samples　fortified　in　the　range　of　0.　010　-5.　0　mg/kg　were　in　the　ranges　of　82%　-　96%　and　3.　2%　-　11.　8%,　respectively.　Good　linearity　was　obtained　in　the　concentration　range　from　0.　050　to　50.　0　mg/L.　The　limit　of　detection　was　0.　010　mg/kg.　The　proposed　method　was　successfully　applied　to　the　analysis　of　quinoxyfen　residue　in　various　food　samples.