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Abstract：
Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic acids-based analysis have been widely applied in biological studies, clinical diagnosis, environmental analysis, food safety and forensic analysis. During the past decades, the field of nucleic acids analysis has been rapidly advancing with many technological breakthroughs. In this review, we focus on the methods developed for analyzing nucleic acids, nucleic acids-based analysis, device for nucleic acids analysis, and applications of nucleic acids analysis. The representative strategies for the development of new nucleic acids analysis in this field are summarized, and key advantages and possible limitations are discussed. Finally, a brief perspective on existing challenges and further research development is provided.
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SCIENCE CHINA-CHEMISTRY
ISSN： 1674-7291
CN： 11-5839/O6
Year： 2020
Issue： 2
Volume： 64
Page： 171-203
9 . 4 4 5
JCR@2020
1 0 . 4 0 0
JCR@2023
ESI Discipline： CHEMISTRY;
ESI HC Threshold：160
JCR Journal Grade：1
CAS Journal Grade：2
Cited Count：
WoS CC Cited Count： 182
SCOPUS Cited Count： 97
ESI Highly Cited Papers on the List： 21 Unfold All
WanFang Cited Count：
Chinese Cited Count：
30 Days PV： 1
Affiliated Colleges：
