• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
成果搜索

author:

Zeng, Zhiyao (Zeng, Zhiyao.) [1] | Tang, Juan (Tang, Juan.) [2] | Zhang, Ming (Zhang, Ming.) [3] | Pu, Shouzhi (Pu, Shouzhi.) [4] | Tang, Dianping (Tang, Dianping.) [5] (Scholars:唐点平)

Indexed by:

EI SCIE

Abstract:

Herein, a novel signal-on photoelectrochemical (PEC) biosensor with nearly zero background noise (ZBN) was first fabricated to determine the presence of organophosphorus pesticide based on in situ formation of DNA-templated Ag2S photoactive materials, accompanied by hybridization chain reaction (HCR) signal amplification. The capture probe (S1) on the gold nanoparticle-modified electrode can hybridize with the aptamer molecule to generate a simple PEC biosensor. In the presence of a target molecule, the aptamer molecule is released on the double-stranded DNA (dsDNA)-modified PEC biosensor. Meanwhile, the capture probe remains on the electrode and can open the DNA hairpins (H1, H2) which are rich in cytosine, to trigger the HCR reaction. The rich "C" strands are uncovered after formation of a long dsDNA polymer strand, which can assemble multiple silver ions (Ag+) by means of by C-Ag+-C chelation. Then, a large number of Ag2S can be generated by challenging with S2- solution, producing a satisfactory photocurrent signal. The photoactive material is formed in situ, which eliminates the laborious operation. Moreover, the signal can be highly amplified with nearly zero background noise and HCR signal amplification. Under optimal conditions, the ZBN aptasensor exhibited high sensitivity and selectivity, with a low detection limit of 2 pg mL(-1) for malathion. Importantly, the sensing platform can also be applied to determine the presence of malathion in real samples.

Keyword:

Ag2S Hybridization chain reaction Malathion Photoelectrochemical aptasensor Zero background

Community:

  • [ 1 ] [Zeng, Zhiyao]Jiangxi Normal Univ, Key Lab Green Chem Jiangxi Prov, Key Lab Funct Small Mol, Minist Educ, 99 Ziyang Ave, Nanchang 330022, Jiangxi, Peoples R China
  • [ 2 ] [Tang, Juan]Jiangxi Normal Univ, Key Lab Green Chem Jiangxi Prov, Key Lab Funct Small Mol, Minist Educ, 99 Ziyang Ave, Nanchang 330022, Jiangxi, Peoples R China
  • [ 3 ] [Zhang, Ming]Jiangxi Normal Univ, Key Lab Green Chem Jiangxi Prov, Key Lab Funct Small Mol, Minist Educ, 99 Ziyang Ave, Nanchang 330022, Jiangxi, Peoples R China
  • [ 4 ] [Tang, Juan]Jiangxi Key Lab Organ Chem, Nanchang 330013, Jiangxi, Peoples R China
  • [ 5 ] [Pu, Shouzhi]Jiangxi Key Lab Organ Chem, Nanchang 330013, Jiangxi, Peoples R China
  • [ 6 ] [Tang, Dianping]Fuzhou Univ, Dept Chem, Key Lab Anal & Detect Food Safety, Minist Educ China & Fujian Prov, Fuzhou 350108, Fujian, Peoples R China

Reprint 's Address:

  • [Tang, Juan]Jiangxi Normal Univ, Key Lab Green Chem Jiangxi Prov, Key Lab Funct Small Mol, Minist Educ, 99 Ziyang Ave, Nanchang 330022, Jiangxi, Peoples R China;;[Tang, Juan]Jiangxi Key Lab Organ Chem, Nanchang 330013, Jiangxi, Peoples R China

Show more details

Related Keywords:

Source :

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

ISSN: 1618-2642

Year: 2021

Issue: 25

Volume: 413

Page: 6279-6288

4 . 4 7 8

JCR@2021

3 . 8 0 0

JCR@2023

ESI Discipline: CHEMISTRY;

ESI HC Threshold:117

JCR Journal Grade:2

CAS Journal Grade:2

Cited Count:

WoS CC Cited Count: 11

SCOPUS Cited Count: 11

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

Online/Total:164/10018772
Address:FZU Library(No.2 Xuyuan Road, Fuzhou, Fujian, PRC Post Code:350116) Contact Us:0591-22865326
Copyright:FZU Library Technical Support:Beijing Aegean Software Co., Ltd. 闽ICP备05005463号-1