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author:

Wan, Qian (Wan, Qian.) [1] | Chen, Liang (Chen, Liang.) [2] | Li, Shiwu (Li, Shiwu.) [3] | Kang, Qiang (Kang, Qiang.) [4] | Yuan, Yaofeng (Yuan, Yaofeng.) [5] (Scholars:袁耀锋) | Du, Yu (Du, Yu.) [6]

Indexed by:

SCIE

Abstract:

An asymmetric [3 + 2]-cycloaddition reaction of alpha,beta-unsaturated 2-acyl imidazoles with spirovinylcyclopropanyl-2-oxindoles catalyzed synergistically by an achiral palladium(0) catalyst and a chiral-at-metal rhodium(III) complex has been developed. A series of biologically important 3-spirocyclopentane-2-oxindoles with four contiguous stereocenters were synthesized in high yields (up to 99%) with excellent stereoselectivities (up to 99% ee, 20:1 dr).

Keyword:

Community:

  • [ 1 ] [Wan, Qian]Fuzhou Univ, Coll Chem, Fuzhou 350108, Peoples R China
  • [ 2 ] [Yuan, Yaofeng]Fuzhou Univ, Coll Chem, Fuzhou 350108, Peoples R China
  • [ 3 ] [Chen, Liang]Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China
  • [ 4 ] [Li, Shiwu]Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China
  • [ 5 ] [Kang, Qiang]Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China
  • [ 6 ] [Du, Yu]Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China

Reprint 's Address:

  • 袁耀锋

    [Yuan, Yaofeng]Fuzhou Univ, Coll Chem, Fuzhou 350108, Peoples R China;;[Du, Yu]Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China

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Source :

ORGANIC LETTERS

ISSN: 1523-7060

Year: 2020

Issue: 24

Volume: 22

Page: 9539-9544

6 . 0 0 5

JCR@2020

4 . 9 0 0

JCR@2023

ESI HC Threshold:160

JCR Journal Grade:1

CAS Journal Grade:1

Cited Count:

WoS CC Cited Count: 23

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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