Laser　welding　of　dissimilar　titanium/aluminum　alloys　has　been　employed　at　an　increasing　rate,　particularly　in　the　aerospace　industry,　owing　to　its　advantages　in　terms　of　current　design　flexibility　and　fuel/cost　savings.　The　major　problem　with　dissimilar　Ti/Al　welds　arises　from　the　difference　in　the　thermal　expansion　and　contraction　of　the　two　metals,　which　leads　to　hot-cracking　susceptibility　and　the　mitigation　of　the　mechanical　property　after　welding.　In　the　present　study,　pulsed　Nd:YAG　laser　welding　of　Ti6Al4V　and　AA6060　has　been　addressed.　Hot-cracking　susceptibility　in　the　heat　affected　zone　and　the　shear　fracture　behavior　of　the　lap　joints　were　investigated　through　microstructural　characterization　and　mechanical　tests.　The　results　indicate　that　the　hot　cracking　tendency　can　be　reduced　by　increasing　the　pulse　peak　power　(7.5-8.5　kW)　and　the　laser　point　diameter　(0.8-1.0　mm)　with　specific　pulse　duration　and　overlap.　An　alternative　control　strategy　for　less　hot　cracks　in　the　Ti/Al　lap　joint　can　be　to　increase　the　weld　width　and　decrease　the　cooling　rate　during　solidification.　The　shear　fracture　of　the　Ti/Al　lap　joint　is　likely　to　occur　along　the　lower　side　path　of　the　weld　interface　with　decreasing　weld　surface　collapsed　amount　and　increasing　aluminum　base　metal　melt　depth.　(c)　2020　Chinese　Society　of　Aeronautics　and　Astronautics.　Production　and　hosting　by　Elsevier　Ltd.　This　is　an　open　access　article　under　the　CC　BY-NC-ND　license　(http://creativecommons.org/licenses/by-nc-nd/4.0/).