Catalytic　conversion　of　propane　to　propylene　can　be　achieved　by　non-oxidative　propane　dehydrogenation　(PDH)　by　Pt-based　catalysts　under　550–700　°C.　In　this　work,　we　report　a　strategy　to　decrease　the　Pt　loading　amount　to　only　0.1　wt%　for　obtaining　a　stable　catalyst　via　silica　coating　for　high　PDH　activity　at　a　temperature　as　low　as　of　450　°C.　The　as-prepared　2.5%Si@PtGa/Al2O3　catalyst　shows　outstanding　catalytic　activity　(propylene　productivity　rate　0.5　mol/gcat.·h)　close　to　its　equilibrium　conversion　(24.5%)　with　much　better　stability　(deactivation　constant:　0.007　h−1)　at　450　°C.　The　interface　between　catalyst　and　silica　coating　changes　the　strong　metal-support　interaction　(SMSI)　to　immobilize　the　Ga　oxide　clusters,　further　tightly　anchoring　the　Pt　catalytic　sites　for　PDH　process.　Moreover,　the　electronic　state　of　Pt　is　also　influenced　by　the　silica　coating　layers.　This　work　demonstrates　a　new　method　to　harnessing　the　metal-support　interaction　in　catalysis.　©　2021　Elsevier　B.V.