Reversible　chemical　reaction　has　an　important　effect　on　lithium-ion　intercalation/deintercalation　and　the　stress　distribution.　Reversible　chemical　reaction,　diffusion　and　electrode　deformation　will　strongly　interact　with　each　other.　In　this　work,　considering　the　reversible　chemical　reaction　and　its　effect　on　the　diffusion　and　stress,　a　fully　coupled　reversible　reaction-diffusion-mechanical　model　is　developed,　which　evaluates　reversible　reaction-diffusion-induced　stresses.　Two　key　parameters,　n　(the　ratio　of　forward　and　backward　reaction　coefficient)　and　Thiele　number　(the　ratio　of　forward　reaction　and　diffusion)　are　used　to　characterize　their　effects　on　the　charge　and　stress　under　potentiostatic　operation.　Numerical　results　show　that　(1)　the　forward　chemical　reaction　decreases　the　charge　and　promotes　the　deformation　and　(2)　the　backward　reaction　is　needed　to　improve　the　charge　and　prevent　the　electrode　damage.　©　2021　John　Wiley　&　Sons　Ltd