Stretchable　organic　transistors　possess　great　potential　in　a　variety　of　emerging　areas　such　as　biomedical　electronics,　wearable　gadgets　and　smart　skin.　Here,　stretchable　vertical　organic　field　effect　transistor　(s-VOFET)　is　developed　for　the　first　time,　which　exhibits　low　working　voltage　(−0.5　V),　high　current　density　(5.19　mA/cm2)　and　excellent　stretching　stability.　More　interesting,　the　on　state　current　increased　by　68.5%　and　the　sub-threshold　swing　decreased　by　25.2%　with　the　increase　of　the　strain　to　20%.　It　is　ascribed　to　the　enhanced　face-on　orientation　of　π-π　stacking　in　semiconductor　film　by　stretching　strain,　providing　more　efficient　pathways　for　vertical　charge　transport.　Meanwhile,　simulation　results　demonstrate　that　stretching　strain　can　enhance　gate　field　controllability　to　charge　carriers,　resulting　in　enhanced　charge　transport　and　accumulation.　Moreover,　stretchable　vertical　synaptic　transistor　(s-VST)　is　fabricated　by　replacing　cross-linked　PVA　with　ion　gel,　which　exhibits　stable　synaptic　characteristics　even　with　60%　stretching　strain.　Noticeably,　coupling　triboelectric　nanogenerator　(TENG)　and　synaptic　transistor　leads　to　a　new　field　of　triboelectric,　which　enables　the　direct　interactions　between　environmental　perception　data　and　human-machine　interfacing.　Therefore,　a　stretchable　self-powered　neurologically　integrated　artificial　tactile　pathway　is　constructed　using　TENG　and　s-VST,　which　successfully　conducts　touch　wireless　communication　and　sensory　skin　touch-interaction.　This　work　provides　critical　guidelines　for　the　development　of　high　performance　stretchable　electronic　devices　and　a　new　platform　for　enabling　neurological　functions　in　stretchable　electronics.　©　2021