Treatment　temperature　distribution　is　a　crucial　factor　for　magnetic　hyperthermia,　since　it　directly　determines　the　treatment　effect　related　to　the　apoptosis　situation　of　malignant　cells.　The　shape　of　magnetic　nanoparticles　(MNPs)　is　one　of　many　factors　that　can　affect　the　treatment　temperature　during　therapy.　This　paper　conducts　a　comparative　study　on　three　different　shapes　of　MNPs　by　considering　the　effective　area　percentage　of　treatment　temperature　distribution.　The　treatment　temperature　for　a　proposed　model　is　predicted　by　solving　bio-heat　transfer　equations,　which　take　the　power　dissipation　of　MNPs　as　the　input　and　consider　a　temperature-dependent　blood　perfusion　rate　in　these　equations　at　the　same　time.　The　simulation　results　demonstrate　that　the　treatment　temperature　distribution　can　be　effectively　improved　when　the　temperature-dependent　blood　perfusion　rate　is　used　for　the　simulation　with　respect　to　a　constant　case.　In　addition,　the　MNPs　with　higher　regular　shape　can　lead　to　a　better　result　than　a　lower　case　in　the　treatment　temperature　distribution　when　the　same　condition　is　considered　for　therapy.　©　2021　IOP　Publishing　Ltd.