Exploring　new　ways　to　acquire　niobium　resources　is　essential　to　resolve　niobium　supply　risks,　due　to　the　fact　that,　at　present,　99%　of　niobium　is　controlled　by　only　two　countries.　In　the　present　work,　a　flotation　technique　was　applied　to　separate　niobium　from　low-grade　niobite　ore.　To　maximize　the　utilization　of　the　original　ore　resources,　pre-flotation　was　conducted　to　recover　sulfur　and　eliminate　the　adverse　effects　of　sulfide　on　niobite　flotation.　The　obtained　sulfur　grade　and　recovery　were　33.74%　and　92.04%,　respectively,　and　its　concentration　ratio　was　40x.　As　for　the　niobite　flotation,　a　closed-circuit　experiment　with　one　rougher　flotation,　three　cleaner　flotations,　and　two　scavenger　flotations　was　carried　out　to　achieve　the　maximum　niobite　recovery.　To　further　improve　the　niobite　recovery,　a　leaching　process　with　diluted　HCl　was　employed;　the　final　obtained　Nb2O5　grade　and　recovery　were　30.19%　and　65.04%,　respectively,　and　the　concentration　ratio　reached　242x.　Moreover,　the　economic　evaluation　implies　that　the　flotation　process　can　attract　great　positive　interest.