The　reasonable　employment　of　cocatalyst　in　photocatalysis　can　effectively　promote　the　photocatalytic　H2　production　activity.　In　this　study,　carbon　hollow　spheres　(C),　as　a　good　conductive　nonmetallic　material,　have　been　utilized　as　a　novel　cocatalyst　and　a　matrix　for　loading　the　Cu-doped-TiO2　nanoparticles　by　a　successive　hydrothermal　method　and　metal　molten　salt　method.　The　Cu-doped-TiO2　nanoparticles　were　tightly　anchored　on　the　surface　of　carbon　hollow　sphere　to　form　a　zero-dimensional/three　dimensional　(0D/3D)　Cu-doped-TiO2/C　heterojunction.　The　optimal　Cu-doped-TiO2/C　heterojunction　demonstrated　greatly　enhanced　photocatalytic　H2　generation　activity　(14.4 mmol·g−1·h−1)　compared　with　TiO2　(0.33 mmol·g−1·h−1)　and　TiO2/C　(0.7 mmol·g−1·h−1).　The　performance　improvement　was　mainly　due　to　the　synergistic　effect　of　carbon　hollow　sphere　cocatalyst　and　Cu-doping,　the　Cu-doping　in　TiO2　nanoparticles　can　minimize　charge　recombination　and　enhance　the　available　photoexcited　electrons,　while　the　3D　carbon　hollow　spheres　can　act　as　electron　traps　to　accelerate　the　charge　separation　and　offer　abundant　active　sites　for　solar　water　splitting　reaction.　Graphical　abstract:　[Figure　not　available:　see　fulltext.]　©　2022,　Youke　Publishing　Co.,Ltd.