The　commercial　viability　of　lithium–sulfur　batteries　is　still　challenged　by　the　notorious　lithium　polysulfides　(LiPSs)　shuttle　effect　on　the　sulfur　cathode　and　uncontrollable　Li　dendrites　growth　on　the　Li　anode.　Herein,　a　bi-service　host　with　Co-Fe　binary-metal　selenide　quantum　dots　embedded　in　three-dimensional　inverse　opal　structured　nitrogen-doped　carbon　skeleton　(3DIO　FCSe-QDs@NC)　is　elaborately　designed　for　both　sulfur　cathode　and　Li　metal　anode.　The　highly　dispersed　FCSe-QDs　with　superb　adsorptive-catalytic　properties　can　effectively　immobilize　the　soluble　LiPSs　and　improve　diffusion-conversion　kinetics　to　mitigate　the　polysulfide-shutting　behaviors.　Simultaneously,　the　3D-ordered　porous　networks　integrated　with　abundant　lithophilic　sites　can　accomplish　uniform　Li　deposition　and　homogeneous　Li-ion　flux　for　suppressing　the　growth　of　dendrites.　Taking　advantage　of　these　merits,　the　assembled　Li–S　full　batteries　with　3DIO　FCSe-QDs@NC　host　exhibit　excellent　rate　performance　and　stable　cycling　ability　(a　low　decay　rate　of　0.014%　over　2,000　cycles　at　2C).　Remarkably,　a　promising　areal　capacity　of　8.41　mAh　cm−2　can　be　achieved　at　the　sulfur　loading　up　to　8.50 mg cm−2　with　an　ultra-low　electrolyte/sulfur　ratio　of　4.1　μL　mg−1.　This　work　paves　the　bi-serve　host　design　from　systematic　experimental　and　theoretical　analysis,　which　provides　a　viable　avenue　to　solve　the　challenges　of　both　sulfur　and　Li　electrodes　for　practical　Li–S　full　batteries.[MediaObject　not　available:　see　fulltext.]　©　2023,　The　Author(s).