Diabetic　foot　(DF)　is　difficult　to　heal　due　to　the　formation　of　drug-resistant　bacterial　biofilms　and　dysregulation　of　the　wound　microenvironment.　To　solve　this　problem,　multifunctional　hydrogels　were　prepared　by　in　situ　or　spraying　with　3-aminophenylboronic　acid　modified　oxidized　chondroitin　sulfate　(APBA-g-OCS),　polyvinyl　alcohol　(PVA)　and　black　phosphorus/bismuth　oxide/Ε-polylysine　(BP/Bi2O3/Ε-PL)　as　precursors　for　promoting　infected　diabetic　wounds　healing.　The　hydrogels　display　multiple　stimulus　responsiveness,　strong　adhesion　and　rapid　self-healing　ability　owing　to　the　dynamic　borate　ester　bonds,　hydrogen　bonds　and　π-π　conjugation　cross-link　points,　remain　synergistic　chemo-photothermal　antibacterial　effect　and　anti-biofilm　formation　ability　due　to　the　doping　of　BP/　Bi2O3/Ε-PL　into　the　hydrogel　by　dynamic　imine　bonds　crosslinking　and　possess　anti-oxidation　and　inflammatory　chemokine　adsorption　ability　attributing　to　the　presence　of　APBA-g-OCS.　Most　importantly,　as　a　result　of　the　above　functions,　the　hydrogels　can　not　only　respond　to　the　wound　microenvironment　to　conduct　combined　PTT　and　chemotherapy　for　efficient　anti-inflammation,　but　also　improve　the　wound　microenvironment　by　scavenging　ROS　and　regulating　the　expression　of　cytokines,　thus　further　accelerating　collagen　deposition,　promoting　granulation　tissue　formation　and　angiogenesis,　finally　promoting　the　healing　of　infected　wounds　in　diabetic　rats.　©　2023