There　are　approximately　4　billion　tons　of　uranium　in　the　ocean,　which　is　unmatched　by　the　surface.　Nevertheless,　it＇s　very　challenging　to　extract　uranium　from　the　ocean　due　to　the　exceedingly　low　concentration　of　uranium　in　the　ocean　(about　3.3　μg　L−1)　as　well　as　high　salinity　level.　Current　methods　are　often　limited　by　selectivity,　sustainability,　economics,　etc.　Herein,　phosphoric　acid　group　and　amidoxime　group　were　grafted　to　skin　collagen　fibers　through　＇　initiated　access＇　to　design　a　new　uranium　extraction　material,　abbreviated　as　CGPA.　Through　laboratory　simulation　experiments,　it　is　concluded　that　the　maximum　adsorption　capacity　of　CGPA　for　uranium　reaches　263.86　mg　g−1.　It　has　high　adsorption,　selectivity,　and　reusability　for　uranium.　In　the　actual　seawater　extraction　experiment,　CGPA　obtained　29.64　μg　of　uranium　after　extracting　10.0　L　of　seawater,　and　the　extraction　rate　was　90.1%.　The　adsorbent　has　excellent　effects　in　kinetics,　selectivity,　extraction　capacity,　renewability,　etc.　In　the　extraction　of　uranium　from　seawater,　and　is　an　economically　feasible　and　industrially　expandable　adsorbent.　©　2023　Elsevier　Ltd