Ocean　reserves　massive　water　and　mineral　resources.　The　success　in　uranium　extraction　and　desalination　from　seawater　is　expected　to　alleviate　the　severe　situation　of　energy　and　freshwater　scarcities　around　the　world.　Herein,　a　novel　Janus　photothermal　adsorbent　was　fabricated　via　sequential　electrospinning　for　simultaneous　uranium　extraction　and　co-production　of　freshwater　and　sea　salt　from　seawater.　It　consisted　of　a　hydrophilic　polyamidoxime　(PAO)　nanofibrous　mat　as　the　bottom　layer　for　uranyl　ion　adsorption　and　a　hydrophobic　polyvinylidene　fluoride　(PVDF)/MXene　(Ti3C2Tx)　composite　nanofibrous　mat　as　the　upper　layer　to　capture　and　convert　solar　energy　to　heat.　With　the　assistance　of　1-sun　illumination,　the　Janus　adsorbent　exhibited　6.05　mg　g-1　of　uranium　adsorption　capacity　within　28　days　from　natural　seawater,　resulting　in　a　30.1　%　increase　compared　to　that　in　dark　and　achieved　1.36　kg　m-2h-　1　of　water　evaporation　rate　in　natural　seawater.　An　outdoor　solar-powered　adsorption　coupling　with　evaporation　test　of　this　Janus　adsorbent　demonstrates　that　6.40　kg　m-　2　of　freshwater,　2.02　mg　m-　2　of　uranium　and　0.22　kg　m-　2　of　sea　salt　were　co-produced　within　9　h　operation.　This　study　on　the　Janus　adsorbent　paves　a　promising　way　to　the　comprehensive　development　of　ocean　resources　in　low-carbon　and　sustainable　strategy.