Due　to　its　significant　biocompatibility　and　environmental　friendliness,　the　composite　of　heterojunction　photo-catalyst　and　natural　protein　is　a　promising　material　in　the　field　of　photocatalysis.　For　the　first　time,　direct　Z-scheme　Bi2MoO6/Ag3PO4　composites　with　different　concentrations　of　Ag3PO4　were　successfully　fabricated　by　an　in-situ　deposition　method,　and　Bi2MoO6/Ag3PO4@silk　fibroin　(BMO/APO@SF)　films　were　further　constructed　by　electrospinning　technology　to　explore　the　photocatalytic　activity　of　heterojunction　photocatalysts.　The　results　of　various　characterizations　confirmed　that　improved　photocatalytic　performance,　including　efficient　charge　sep-aration,　and　a　widened　visible　light　absorption　range,　could　be　attributed　to　the　formation　of　a　heterojunction　structure　between　Bi2MoO6　and　Ag3PO4,　which　considerably　promoted　photocatalytic　activity　for　ciprofloxacin　(CIP)　degradation.　According　to　the　analysis　of　degradation　products　measured　by　Q-TOF,　possible　CIP　degra-dation　pathways　were　proposed.　Density　functional　theory　(DFT)　calculation　and　Laplacian　bond　order　(LBO)　analysis　were　consistent　with　the　results　of　Q-TOF.　Through　trapping　experiments,　the　significant　contribution　of　O-center　dot(2)-　to　BMO/APO@SF　was　demonstrated.　Moreover,　the　antibacterial　rates　of　Bi2MoO6/15Ag(3)PO(4)@SF　(BMO/15APO@SF)　against　Escherichia　coli　and　Staphylococcus　aureus　were　greater　than　94.36%　and　95.72%,　respec-tively,　indicating　that　BMO/15APO@SF　had　excellent　antibacterial　performance.