It　is　of　great　interest　to　develop　a　simple,　general,　and　easy-handling　procedure　for　mesoporous　silica　coating.　A　facile,　single-step　method　to　coat　iron　oxide　nanoparticles　has　been　reported　by　Hyeon＇s　group.　However,　up　to　present,　this　method　only　successfully　applied　to　those　zero-dimensional　nanostructures　heavily　capped　by　cetyltrimethyl　ammonium　bromide　(CTAB);　no　others　are　reported.　It　is　unknown　how　this　simple　method　is　feasible　in　coating　those　nanostructures　not　capped　by　CTAB.　Herein,　using　carbon　nanotubes　(CNTs)　as　the　model,　through　an　analogous　layer-by-layer　assembly　method,　many　more　CTAB　molecules　were　found　to　anchor　to　CNTs,　on　which　uniform　rnesoporous　silica　shells　can　successfully　be　formed　by　Hyeon＇s　coating　method.　We　believe　that　this　contribution　will　pave　the　way　for　advancing　the　single-step　method　to　become　a　general　protocol　in　the　mesoporous　silica　coating　field.