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author:

Zhou Jing (Zhou Jing.) [1] | Zhang Xiaolan (Zhang Xiaolan.) [2] | Yu Zhiqiang (Yu Zhiqiang.) [3] | Wu Minghong (Wu Minghong.) [4] (Scholars:吴明红) | Yang Zujing (Yang Zujing.) [5] | Sheng Guoying (Sheng Guoying.) [6] | Fu Jiamo (Fu Jiamo.) [7]

Indexed by:

CPCI-S

Abstract:

The internal exposures to polycyclic aromatic hydrocarbons (PAHs) of pregnant women from Shanghai were assessed through the detection of urinary PAHs metabolites. Several monohydroxylated PAHs (OH-PAHs) were monitored, and the mean concentrations of 2-Hydroxynaphthatene (2-OHNap), 2-Hydroxyfluorene (2-OHFlu) and 1-Hydroxypyrene (1-OHPyr) were 0.57 mu g/mmol creatinine, 0.32 mu g/mmol creatinine and 0.06 mu g/mmol creatinine, respectively. Relative high concentrations, especial 2-OHFlu, can be found in Shanghai compared with previous studies. The profile of different OH-PAHs was calculated and 2-OHNap was the main component. The concentration of 1-OHPyr is almost one order of magnitude lower than that of 2-OHNap. All the correlation studies indicate that monitoring of 2-OHNap, 2-OHFlu and 1-OHPyr as multiple biomarkers are more suitable than 1-OHPyr. Smoking can obviously affect the concentration level of 2-OHNap in urine samples, but no significant difference is observed between levels of 2-OHFlu and 1-OHPyr in smokers and nonsmokers. The concentration of 2-OHNap seems to be more sensitive to cigarette smoke than other analytes.

Keyword:

HPLC monohydroxy-PAH metabolites pregnant woman urine

Community:

  • [ 1 ] [Zhou Jing]Shanghai Univ, Sch Environm & Chem Engn, Inst Environm Pollut & Hlth, Shanghai 200444, Peoples R China
  • [ 2 ] [Zhang Xiaolan]Shanghai Univ, Sch Environm & Chem Engn, Inst Environm Pollut & Hlth, Shanghai 200444, Peoples R China
  • [ 3 ] [Wu Minghong]Shanghai Univ, Sch Environm & Chem Engn, Inst Environm Pollut & Hlth, Shanghai 200444, Peoples R China
  • [ 4 ] [Sheng Guoying]Shanghai Univ, Sch Environm & Chem Engn, Inst Environm Pollut & Hlth, Shanghai 200444, Peoples R China
  • [ 5 ] [Fu Jiamo]Shanghai Univ, Sch Environm & Chem Engn, Inst Environm Pollut & Hlth, Shanghai 200444, Peoples R China

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Source :

PROGRESS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, VOL II, PTS A AND B

Year: 2009

Page: 2384-2389

Cited Count:

WoS CC Cited Count: 3

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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