Photocatalytic　water　purification　is　an　efficient　environmental　protection　method　that　can　be　used　to　eliminate　toxic　and　harmful　substances　from　industrial　effluents.　However,　the　TiO2-based　catalysts　currently　in　use　absorb　only　a　small　portion　of　the　solar　spectrum　in　the　ultraviolet　(UV)　region,　resulting　in　lower　efficiency.　In　this　paper,　we　demonstrate　a　molybdenum　disulfide/zeolitic　imidazolate　framework-8　(MoS2/ZIF-8)　composite　photocatalyst　that　increases　the　photocatalytic　degradation　of　ciprofloxacin　(CIP)　and　tetracycline　hydrochloride　(TC)　by　factors　of　1.21　and　1.07,　respectively.　The　transformation　products　of　CIP　and　TC　from　the　catalysis　processes　are　tentatively　identified,　with　the　metal-organic　framework　(MOF)　being　considered　to　be　the　main　active　species　with　holes　being　considered　as　the　main　active　species.　The　hydrogen　production　rate　of　the　MoS2/ZIF-8　nanocomposites　is　1.79　times　higher　than　that　of　MoS2.　This　work　provides　a　novel　perspective　for　exploring　original　and　efficient　1T/2H-MoS2/MOF-based　photocatalysts　by　optimizing　the　construction　of　surface　nano-heterojunction　structures.　The　composite　photocatalyst　is　found　to　be　durable,　with　its　catalytic　performance　being　preserved　under　stability　testing.　Thus,　1T/2H-MoS2/MOF-based　photocatalysts　have　excellent　prospects　for　practical　antibiotic-degradation　engineering.　(C)　2019　THE　AUTHORS.　Published　by　Elsevier　LTD　on　behalf　of　Chinese　Academy　of　Engineering　and　Higher　Education　Press　Limited　Company.