Herein,　the　occurrence　of　three　Hexabromocyclododecane　(HBCDD)　diastereoisomers　in　soil　and　road　dust　from　the　mixed-land-use　areas　in　Shanghai　was　investigated.　The　total　concentrations　of　HBCDDs　(Sigma　HBCDDs)　in　soil　ranged　from　0.30　to　249　ng　g(-1)　dw,　with　a　median　level　of　5.14　ng　g(-1)　dw.　For　the　road　dust　samples,　the　Sigma　HBCDD　concentrations　varied　from　4.11　to　508　ng　g(-1)　dw,　with　a　median　level　of　23.4　ng　g(-1)　dw.　The　levels　of　HBCDDs　varied　in　different　mixed-land-use　areas.　In　soil,　the　levels　of　HBCDDs　increased　in　the　following　sequence:　residential　area　&　agricultural　area　(R&A)　＜　agricultural　area　&　industrial　area　(A&I)　＜　residential　area　&　commercial　area　(R&C)　＜　residential　area　&　industrial　area　(R　&　the　levels　for　the　road　dust　were　A&I　＜　R&A　＜　R&C　＜　R&I.　The　proportions　of　alpha-HBCDD　in　road　dust　samples　were　significantly　higher　than　those　of　alpha-HBCDD　in　the　soil.　For　soil,　the　portion　of　alpha-HBCDD　increased　in　the　following　sequence:　R&I　＜　A&I　approximate　to　R&A　＜　R&C,　while　that　for　the　road　dust　was　R&C　＜　R&A　＜　R&I　＜　A&I.　Significant　correlations　in　the　concentrations　of　HBCDDs　between　soil　and　road　dust　from　R&C　and　R&I　were　found,　which　suggested　that　they　may　share　similar　sources　in　these　regions.　On　the　basis　of　the　HBCDD　concentrations　of　road　dust　and　soil,　the　contributions　of　ingestion,　dermal　contact　absorption　and　inhalation　intake　to　total　estimated　daily　intakes　(EDIs)　were　estimated.　The　highest　total　EDIs　of　Sigma　HBCDDs　(sum　of　ingestion,　dermal　contact　absorption　and　inhalation　intake)　were　0.154,　7.5　x　10(-2)　ng　kg(-1)　d(-1)　for　infants　from　road　dust　and　soil　in　R&I,　respectively.　(C)　2016　Elsevier　B.V.　All　rights　reserved.