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author:

Zhang, Zhaokang (Zhang, Zhaokang.) [1] | Huang, Lu (Huang, Lu.) [2] | Chen, Yiting (Chen, Yiting.) [3] | Qiu, Zhenli (Qiu, Zhenli.) [4] | Meng, Xiangying (Meng, Xiangying.) [5] | Li, Yanxia (Li, Yanxia.) [6]

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EI Scopus SCIE

Abstract:

In this work, a portable electrochemical glucose sensor was studied based on a laser-induced graphene (LIG) composite electrode. A flexible graphene electrode was prepared using LIG technology. Poly(3,4-ethylene dioxythiophene) (PEDOT) and gold nanoparticles (Au NPs) were deposited on the electrode surface by potentiostatic deposition to obtain a composite electrode with good conductivity and stability. Glucose oxidase (GOx) was then immobilized using glutaraldehyde (GA) to create an LIG/PEDOT/Au/GOx micro-sensing interface. The concentration of glucose solution is directly related to the current value by chronoamperometry. Results show that the sensor based on the LIG/PEDOT/Au/GOx flexible electrode can detect glucose solutions within a concentration range of 0.5 x 10-5 to 2.5 x 10-3 mol L-1. The modified LIG electrode provides the resulting glucose sensor with an excellent sensitivity of 341.67 mu A mM-1 cm-2 and an ultra-low limit of detection (S/N = 3) of 0.2 x 10-5 mol L-1. The prepared sensor exhibits high sensitivity, stability, and selectivity, making it suitable for analyzing biological fluid samples. The composite electrode is user-friendly, and can be built into a portable biosensor device through smartphone detection. Thus, the developed sensor has the potential to be applied in point-of-care platforms such as environmental monitoring, public health, and food safety. In this work, a portable electrochemical glucose sensor was studied based on a laser-induced graphene (LIG)/PEDOT/Au/GOx micro-sensing interface.

Keyword:

Community:

  • [ 1 ] [Zhang, Zhaokang]Fuzhou Univ, Coll Chem Engn, Fuzhou 350108, Peoples R China
  • [ 2 ] [Huang, Lu]Minjiang Univ, Coll Mat & Chem Engn, Fuzhou 350108, Peoples R China
  • [ 3 ] [Chen, Yiting]Minjiang Univ, Coll Mat & Chem Engn, Fuzhou 350108, Peoples R China
  • [ 4 ] [Qiu, Zhenli]Minjiang Univ, Coll Mat & Chem Engn, Fuzhou 350108, Peoples R China
  • [ 5 ] [Li, Yanxia]Minjiang Univ, Coll Mat & Chem Engn, Fuzhou 350108, Peoples R China
  • [ 6 ] [Meng, Xiangying]Weifang Med Univ, Sch Med Lab, Weifang 261053, Peoples R China

Reprint 's Address:

  • [Li, Yanxia]Minjiang Univ, Coll Mat & Chem Engn, Fuzhou 350108, Peoples R China;;[Meng, Xiangying]Weifang Med Univ, Sch Med Lab, Weifang 261053, Peoples R China

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RSC ADVANCES

ISSN: 2046-2069

Year: 2024

Issue: 2

Volume: 14

Page: 1034-1050

3 . 9 0 0

JCR@2023

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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