The　poor　mechanical　properties　exhibited　by　pure　Zn　effectively　prohibit　its　utilization　as　a　viable　material　for　biodegradable　implants.　Hence,　the　primary　area　of　interest　has　been　directed　towards　alloy　design　and　process　strategies　of　biodegradable　Zn　alloys.　To　this　end,　novel　biodegradable　Zn-xCu-xTi　(Cu:　x　=　0.001　-　2.72　and　Ti:　x　=　0.03　-　1.21)　alloys　were　designed　and　fabricated　using　a　gradient　continuous　casting　method　followed　by　homogenization　and　rolling.　The　fabricated　samples　were　then　investigated　in　terms　of　their　microstructures,　mechanical　properties,　and　corrosion　behavior.　The　results　showed　that　the　as　-cast　Zn-0.001Cu-0.037Ti　and　Zn1.50Cu-1.06Ti　alloys　possess　better　mechanical　properties　and　corrosion　resistance.　The　yield　strength,　elongation,　and　highest　charge　transfer　resistance　(Rct)　of　Zn-0.001Cu-0.037Ti　were　137　MPa,　60　%,　and　2227.9　Omega　,　respectively.　On　the　other　hand,　the　Zn-1.50Cu-1.06Ti　alloy　exhibited　250　MPa　yield　strength,　12.7.%　elongation,　and　11113.0　Omega　Rct,　respectively.　Higher　Cu　and　Ti　content　also　led　to　larger　second　phases.　However,　as　-hot　rolled　Zn-1.50Cu-1.06Ti　alloy　displayed　better　mechanical　properties　as　compared　to　the　Zn-0.001Cu-0.037Ti　alloy　due　to　a　very　fine　nanocrystalline　structure.　Furthermore,　the　hot　-rolled　Zn-xCu-xTi　alloys　demonstrated　superior　corrosion　resistance　compared　to　their　as　-cast　counterparts,　as　evidenced　by　the　analysis　of　the　potentiodynamic　polarization　and　electrochemical　impedance　spectroscopy　data.　This　improved　corrosion　resistance　is　attributed　to　the　refined　grain　size,　fractured　second　phases　which　reduce　both　the　anode　and　cathode　areas,　and　the　formation　of　protective　oxide　layers.　Lastly,　the　corrosion　products　primarily　consisted　of　carbon,　phosphorus,　calcium,　and　oxygen,　suggesting　the　presence　of　Zn(OH)　2　,　carbonates,　and　phosphates.