Given　the　high　solubility　and　mobility　of　hexavalent　chromium　in　the　environment　and　edible　plants,　the　development　of　a　suitable　method　for　the　screening　and　quantification　of　Cr(VI)　is　highly　desirable.　Herein,　a　selective　and　sensitive　sensing　method　for　detecting　Cr(VI)　in　food　grains　was　established,　using　an　electrodeposited　gold-palladium　bimetallic　nanoparticles　(BNPs)　based　electrochemical　sensor　and　a　microwave　digestion　procedure　for　chromium　dissolution.　The　sensor　interface　was　characterized　by　scanning　electron　microscopy　(SEM),　energy-dispersive　X-ray　spectroscopy　(EDX)　and　cyclic　voltammetry.　The　results　indicate　that　the　fabricated　sensor　has　a　larger　active　surface　area　and　an　enhanced　electrocatalytic　effect　compared　to　the　monometallic　modification,　leading　to　a　significant　increase　in　the　electrochemical　reduction　current　of　Cr(VI)　as　a　consequence　of　synergistic　effects.　Using　square　wave　anodic　stripping　voltammetry,　the　sensor　demonstrates　a　wide　linear　range　(5–3000　μg　L−1)　and　a　low　detection　limit　of　2.7　μg　L−1　for　Cr(VI),　as　well　as　considerable　repeatability　and　stability.　Satisfactory　selectivity　towards　Cr(VI)　was　also　demonstrated,　even　in　the　presence　of　500-fold　Cr(III)　and　100-fold　common　heavy　metal　ions　like　Cd(II),　Pb(II),　and　Hg(II).　The　proposed　sensing　method　offers　a　promising　alternative　for　rapidly　identifying　toxic　Cr(VI)　in　water　and　food　grains.　©　2024　Wiley-VCH　GmbH.