Laser　diode　(LD)-pumped　phosphor-converted　near-infrared　(NIR)　lighting　source　predicts　a　“brighter”　future　for　active　imaging　and　non-destructive　detection,　with　improved　imaging　resolution　and　detection　accuracy　to　expand　more　application　scenarios.　To　meet　a　variety　of　requirements　for　LD-pumped　phosphor　color　converters,　herein,　a　novel　CaLu2Mg2Si3O12:Ce3+,　Cr3+,　Nd3+　(CLMS:Ce3+,　Cr3+,　Nd3+)　phosphor-in-glass　film　(PiGF)　sintered　on　sapphire　substrate　(SP)　composite　is　fabricated.　By　introducing　a　rapid　infrared　firing　technique,　the　good　luminescence　properties　of　phosphor　powders　are　maintained　in　the　PiGF　due　to　the　trivial　thermally-aggressive　effect　of　glass　components　on　phosphor　particles.　The　multiple　energy　transfers　(ETs)　among　Ce3+,　Cr3+,　and　Nd3+　enhance　the　NIR　luminescence　of　Cr3+　and　Nd3+,　and　simultaneously　extend　the　spectral　range　to　cover　the　NIR-I　and　NIR-II　regions.　The　luminescent　behaviors　of　samples　are　carefully　examined　under　different　laser　excitation　modes　to　gain　more　insights　into　laser-matter　interaction.　A　watt-level　output　is　achieved　by　applying　appropriate　thermal　and　optical　management.　A　comparative　study　is　performed　on　the　luminescence　saturation　mechanism　of　CLMS:Ce3+,　Cr3+,　Nd3+　PiGF　showing　different　contributions　of　thermal　quenching　and　intensity　quenching　among　these　three　ions.　Finally,　the　application　presentations　confirm　the　great　potential　in　the　fields　of　long-distance　night　vision　and　high-resolution　biological　imaging.　©　2024　Wiley-VCH　GmbH.