Intervertebral　disc　degeneration　(IVDD)　stands　as　the　foremost　contributor　to　low　back　pain　(LBP),　imposing　a　substantial　weight　on　the　world　economy.　Traditional　treatment　modalities　encompass　both　conservative　approaches　and　surgical　interventions;　however,　the　former　falls　short　in　halting　IVDD　progression,　while　the　latter　carries　inherent　risks.　Hence,　the　quest　for　an　efficacious　method　to　reverse　IVDD　onset　is　paramount.　Biomaterial　delivery　systems,　exemplified　by　hydrogels,　microspheres,　and　microneedles,　renowned　for　their　exceptional　biocompatibility,　biodegradability,　biological　efficacy,　and　mechanical　attributes,　have　found　widespread　application　in　bone,　cartilage,　and　various　tissue　engineering　endeavors.　Consequently,　IVD　tissue　engineering　has　emerged　as　a　burgeoning　field　of　interest.　This　paper　succinctly　introduces　the　intervertebral　disc　(IVD)　structure　and　the　pathophysiology　of　IVDD,　meticulously　classifies　biomaterials　for　IVD　repair,　and　reviews　recent　advances　in　the　field.　Particularly,　the　strengths　and　weaknesses　of　biomaterials　in　IVD　tissue　engineering　are　emphasized,　and　potential　avenues　for　future　research　are　suggested.　©　2024　by　the　authors.