Oil　leakage　and　discharge　of　organic　wastewater　have　not　only　threatened　the　ecosystem,　but　also　greatly　aggravated　water　scarcity.　Efficient　separation　of　oil-water　mixture　has　become　a　global　challenge.　To　solve　this　issue,　various　hydrophobic　membranes　with　special　wettability　have　been　developed　in　past　decades.　Among　them,　the　hydrophobic　silicone-modified　membranes　have　attracted　much　attention　due　to　their　low　cost,　easy　processing　and　large-scale　production.　Herein,　recent　progresses　of　hydrophobic　silicone-modified　membranes　for　oil-water　separation　are　reviewed.　Basic　mechanisms　and　principles　for　efficient　oil-water　separation　are　presented　as　a　starting　point　for　the　discussion.　Then,　according　to　the　modified　silicone　polymers　or　molecules,　we　give　a　detail　description　of　their　synthesis　and　briefly　introduce　the　main　reactions　with　the　substrate,　the　typical　grafting　strategy　and　fabricating　methods.　Subsequently,　the　performance　and　oil-water　application　of　various　hydrophobic　membranes　modified　silicone　are　introduced.　Finally,　some　problems　and　challenges　faced　by　silicone　modification　are　summarized　and　present,　and　their　future　development　is　also　prospected.