Mineral　assemblages　containing　Cu-Bi　sulfosalts,　Bi　chalcogenides,　and　Ag-(Au)　tellurides　have　been　identified　in　the　mid-Miocene　Zhibula　Cu　skarn　deposit,　Gangdese　Belt,　southern　Tibet.　Different　mineral　assemblages　from　three　locations　in　the　deposit,　including　proximal　massive　garnet　skarn,　proximal　retrogressed　pyroxene-dominant　skarn　in　contact　with　marble,　and　distal　banded　garnet-pyroxene　skarn　hosted　in　marble,　are　studied　to　constrain　the　evolution　of　the　mineralization.　Hypogene　bornite　contains　elevated　Bi　(mean　6.73　wt.%)　and　co-exists　in　proximal　andradite　skarn　with　a　second　bornite　with　far　lower　Bi　content,　carrollite,　Au-Ag　tellurides　(hessite,　petzite),　and　wittichenite.　This　assemblage　indicates　formation　at　relatively　high　temperatures　(＞400　degrees　C)　and　high　f(S2)　and　f(Te2)　during　prograde-stage　mineralization.　Assemblages　of　Bi　sulfosalts　(wittichenite,　aikinite,　kupc　&　iacute;kite,　and　paderaite)　and　bismuth　chalcogenides　(e.g.,　tetradymite)　in　proximal　pyroxene　skarn　are　also　indicative　of　formation　at　relatively　high　temperatures,　but　at　relatively　lower　f(Te2)　and　f(S2)　conditions.　Within　the　reduced　distal　skarn　(chalcopyrite-pyrrhotite-bearing)　in　marble,　cobalt,　and　nickel　occur　as　discrete　minerals:　cobaltite,　melonite　and　cobaltic　pentlandite.　The　trace　ore　mineral　signature　of　the　Zhibula　skarn　and　the　distributions　of　precious　and　critical　trace　elements　such　as　Ag,　Au,　Co,　Te,　Se,　and　Bi　support　an　evolving　magmatic-hydrothermal　system　in　which　different　parts　of　the　deposit　each　define　ore　formation　at　distinct　local　physicochemical　conditions.　This　is　the　first　report　of　kupc　&　iacute;kite　and　paderaite　from　a　Chinese　location.　Their　compositions　are　comparable　to　other　occurrences,　but　conspicuously,　they　do　not　form　nanoscale　intergrowths　with　one　another.