This　paper　presents　an　implantable　pressure　sensor　readout　system　(IPRO)　which　can　work　at　low　voltage　and　does　not　need　internal　low　dropout　regulator　(LDO).　This　paper　has　made　a　series　of　optimizations　for　power　consumption.　The　power　supply　part　of　the　IPRO　uses　434　MHz　energy　harvesting　(EH),　and　the　corresponding　ultra-low　power　undervoltage　lockout　(UVLO)　circuit　is　used.　The　analog　front-end　(AFE)　and　signal　processing　parts　use　current　mode　and　differential　pseudo　phase　locked　loop　(DPPLL),　which　can　work　stably　under　low　voltage　and　maintain　a　certain　degree　of　accuracy　and　power　rejection　ability.　The　wireless　data　transmission　part　adopts　the　impulse　ultra-wide　band　(IR-UWB)　scheme.　Its　ultra-low　power　consumption　allows　it　to　be　powered　by　a　charge　pump.　In　order　to　further　optimize　power　consumption,　a　simplest　encoding　circuit　suitable　for　the　front-end　output　form　was　proposed,　and　a　power　oscillator　(PO)　with　accelerated　starup　was　used　to　optimize　area　and　power　consumption.　The　system　is　implemented　in　180　nm　Complementary　Metal　Oxide　Semiconductor　(CMOS)　process,　with　a　chip　area　of　1.1　∗1.0　mm＇,　The　measurement　results　indicate　that　the　typical　working　voltage　of　the　IPRO　is　0.8　V,　the　typical　power　consumption　is　11.8　μ　W,　and　the　accuracy　is　1.11　mmHg.　Compared　with　existing　designs,　there　is　a　significant　optimization　in　supply　voltage　and　power　consumption.　©　2024　IEEE.