Mo/HMCM-22　is　one　of　the　candidate　catalysts　for　methane　dehydroaromatization　(MDA)　reaction.　However,　serious　coke　deposition　would　deactivate　the　catalyst,　resulting　in　a　rapid　decrease　of　aromatics　yield.　Here,　we　adjusted　the　acidity　of　MCM-22　zeolite　by　doping　boron　into　the　framework.　Boron　species　replace　some　of　framework　aluminum　and　prompt　aluminum　to　locate　in　sinusoidal　channel.　It　optimizes　the　ratio　of　strong/　weak　Br　&　oslash;nsted　acid,　as　well　as　enhances　the　interaction　between　molybdenum　and　HMCM-22　to　facilitate　the　dispersion　of　molybdenum　species.　After　10　h　of　MDA　reaction,　the　yield　of　aromatics　over　Mo/H[B]MCM-22　(SBR　30)　is　3.5　times　higher　than　that　of　Mo/H[B]MCM-22　(SBR　5).　It　decreases　by　only　4.8　%　in　comparison　to　the　initial　yield.　Meanwhile,　Mo/H[B]MCM-22　(SBR　30)　shows　significantly　better　resistance　to　coke　deposition.　Therefore,　the　established　structure-activity　relationships　provide　valuable　insights　for　future　research　on　the　modification　of　zeolite　acidity　in　methane　dehydroaromatization　reaction.