This　work　reports　the　synthesis　of　CO2/ultraviolet　(UV)　light　dual-responsive　CABC-type　asymmetric　tetrablock　polymers　(CABC-ATP)　based　on　organocatalyzed　reversible　complexation-mediated　radical　polymerization　(RCMP)　with　methyl　methacrylate　(MMA),　2-Propenoic　acid,　2-methyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl　ester　(CMMA),　and　2-(dimethylamino)ethyl　methacrylate　(DMAEMA)　as　block　monomers　by　three　steps.　The　obtained　CABC-ATP　has　controllable　number　average　molecular　weight　(Mn)　and　narrow　molecular　weight　distribution　(Mw/Mn　=　1.18–1.29).　The　hydrodynamic　diameter　and　fluorescence　intensity　were　measured　using　dynamic　light　scattering　coupled　with　fluorescence　assays.　Notably,　the　vesicle　volume　increased　from　an　initial　measurement　of　247.6　nm　to　285.4　nm　post-experiment.　The　initial　fluorescence　emission　intensity　recorded　was　4971,　which　decreased　to　1412　following　the　introduction　of　carbon　dioxide　for　20　min.　Subsequently,　the　fluorescence　intensity　recovered　to　5199　upon　nitrogen　exposure.　The　response　behavior　of　CABC-ATP　to　UV　light　is　due　to　the　cross-linking　of　coumarin-based　monomer,　resulting　in　the　change　of　fluorescence　intensity　at　the　macro　level.　Besides,　the　protonation　of　tertiary　amine　is　promoted　by　the　stimulation　of　CO2,　generating　of　the　change　of　vesicle　volume　at　the　micro　level.　©　2024　Elsevier　B.V.