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author:

Tian, Han (Tian, Han.) [1] | Hu, Yanyu (Hu, Yanyu.) [2] | Wu, Jiajie (Wu, Jiajie.) [3] | Wang, Rixuan (Wang, Rixuan.) [4] | Wang, Jing (Wang, Jing.) [5] | Cai, Xixi (Cai, Xixi.) [6] (Scholars:蔡茜茜) | Chen, Xu (Chen, Xu.) [7] (Scholars:陈旭) | He, Yong (He, Yong.) [8] | Wang, Shaoyun (Wang, Shaoyun.) [9]

Indexed by:

EI Scopus SCIE

Abstract:

3D printing of bio-hydrogel scaffolds are widely used in tissue regeneration. However, due to the ultra-soft properties of bio-hydrogels, it is hard to print them precisely. Here, crystal transduction 3D printing with high fidelity is proposed to address this challenge. A phase-transition bio-inks system with beeswax is developed for crystal transduction, which can accelerate energy consumption and induce soft bio-inks to quickly harden during printing. Interestingly, an interconnected porous hydrogel scaffold can be obtained after washing the crystal beeswax. The porous hydrogel scaffold demonstrated excellent biocompatibility and cell proliferation effect in vitro and is free from defense responses and immunogenicity in vivo. Muscle analog porous scaffolds constructed by high-fidelity 3D printing significantly improve the tissue function recovery of rats with muscle defects, compared with the conventional printed hydrogel with a non-matched shape. These structure-performance design rules create exciting opportunities to customize 3D-printed porous hydrogel scaffolds with high fidelity.

Keyword:

3D printing crystal transformations energy consumptions high fidelity porous hydrogel scaffolds

Community:

  • [ 1 ] [Tian, Han]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 2 ] [Hu, Yanyu]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 3 ] [Wu, Jiajie]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 4 ] [Wang, Rixuan]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 5 ] [Cai, Xixi]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 6 ] [Chen, Xu]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 7 ] [Wang, Shaoyun]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China
  • [ 8 ] [Wang, Jing]Zhejiang Univ, Affiliated Hosp 2, Sch Med, Hangzhou 310009, Zhejiang, Peoples R China
  • [ 9 ] [He, Yong]Zhejiang Univ, Affiliated Hosp 2, Sch Med, Hangzhou 310009, Zhejiang, Peoples R China
  • [ 10 ] [Cai, Xixi]Qingyuan Innovat Lab, Quanzhou 362801, Fujian, Peoples R China
  • [ 11 ] [Chen, Xu]Qingyuan Innovat Lab, Quanzhou 362801, Fujian, Peoples R China
  • [ 12 ] [Wang, Shaoyun]Qingyuan Innovat Lab, Quanzhou 362801, Fujian, Peoples R China
  • [ 13 ] [Cai, Xixi]Fuzhou Inst Oceanog, Marine Green Proc Res Ctr, Fuzhou 350108, Fujian, Peoples R China
  • [ 14 ] [Chen, Xu]Fuzhou Inst Oceanog, Marine Green Proc Res Ctr, Fuzhou 350108, Fujian, Peoples R China
  • [ 15 ] [Wang, Shaoyun]Fuzhou Inst Oceanog, Marine Green Proc Res Ctr, Fuzhou 350108, Fujian, Peoples R China

Reprint 's Address:

  • 汪少芸

    [Wang, Shaoyun]Fuzhou Univ, Coll Chem Engn, Coll Biol Sci & Engn, Fuzhou 350108, Fujian, Peoples R China;;[He, Yong]Zhejiang Univ, Affiliated Hosp 2, Sch Med, Hangzhou 310009, Zhejiang, Peoples R China;;[Wang, Shaoyun]Qingyuan Innovat Lab, Quanzhou 362801, Fujian, Peoples R China;;[Wang, Shaoyun]Fuzhou Inst Oceanog, Marine Green Proc Res Ctr, Fuzhou 350108, Fujian, Peoples R China

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Source :

ADVANCED FUNCTIONAL MATERIALS

ISSN: 1616-301X

Year: 2024

Issue: 8

Volume: 35

1 8 . 5 0 0

JCR@2023

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 6

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