Versatile electrochemical device for oxygen management in precise fermentation applications - Details

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Precision　fermentation　plays　an　important　role　in　the　fields　of　food,　pharmaceuticals,　and　biological　research.　This　process　demands　an　intricate　control　of　the　environmental　oxygen　(O2)　concentration.　Traditional　methods　rely　on　large,　complex,　and　costly　gas　sources　and　controllers.　We　develop　an　electrochemical　O2　conditioner　(EOC)　integrating　all　functions　into　a　compact　device.　By　adjusting　electrochemical　parameters　(voltage　and　current),　the　EOC　enables　precise　O2　control　from　1%　to　99%　and　switching　between　O2　generation　and　removal.　Meanwhile,　it　achieves　rapid　O2　removal　(470　mL/min)　and　generation　(390　mL/min),　with　over　90%　reductions　in　size　and　weight　and　a　substantial　decrease　in　energy　and　time　consumption　(73%　and　33%　reductions,　respectively)　compared　to　pressure　swing　adsorption　(PSA)　systems.　Applied　in　yeast　fermentation,　the　EOC　doubles　alcohol　yield　by　optimizing　aerobic　and　anaerobic　processes.　©　2025　The　Author(s)

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DTI-3: Develop electrochemistry MEA membrane electrode assembly microbial cultivation oxygen precise fermentation

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[ 1 ] [Tan Y.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 2 ] [Ma R.]State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350002, China
[ 3 ] [Jiang M.]Hefei Hualing Co., Ltd, Hefei, 230088, China
[ 4 ] [Mao J.]Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201204, China
[ 5 ] [Mao J.]University of Chinese Academy of Sciences, Beijing, 100049, China
[ 6 ] [Li D.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 7 ] [Zhao C.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 8 ] [Zhou F.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 9 ] [Li P.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 10 ] [Zhang Y.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 11 ] [Jiang Z.]National Synchrotron Radiation Laboratory, University of Science and Technology of China, Anhui, Hefei, 230029, China
[ 12 ] [Lin S.]State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350002, China
[ 13 ] [Wang Z.]Hefei Hualing Co., Ltd, Hefei, 230088, China
[ 14 ] [Zhang Y.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 15 ] [Zhang Y.]Deep Space Exploration Laboratory, University of Science and Technology of China, Hefei, 230026, China
[ 16 ] [Wu Y.]Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, 230001, China
[ 17 ] [Wu Y.]Deep Space Exploration Laboratory, University of Science and Technology of China, Hefei, 230026, China

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Device

ISSN： 2666-9986

Year： 2025

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