The　oxygen　reduction　reaction　(ORR)　is　critical　for　energy　conversion　technologies　like　fuel　cells　and　metal-air　batteries.　However,　advancing　efficient　and　stable　ORR　catalysts　remains　a　significant　challenge.　Iron-based　single-atom　catalysts　(Fe　SACs)　have　emerged　as　promising　alternatives　to　precious　metals.　However,　their　catalytic　performance　and　stability　remain　constrained.　Introducing　a　second　metal　(M)　to　construct　Fe　&　horbar;M　dual-atom　catalysts　(Fe　&　horbar;M　DACs)　is　an　effective　strategy　to　enhance　the　performance　of　Fe　SACs.　This　review　provides　a　comprehensive　overview　of　the　recent　advancements　in　Fe-based　DACs　for　ORR.　It　begins　by　examining　the　structural　advantages　of　Fe　&　horbar;M　DACs　from　the　perspectives　of　electronic　structure　and　reaction　pathways.　Next,　the　precise　synthetic　strategies　for　DACs　are　discussed,　and　the　structure-performance　relationships　are　explored,　highlighting　the　role　of　the　second　metal　in　improving　catalytic　activity　and　stability.　The　review　also　covers　in　situ　characterization　techniques　for　real-time　observation　of　catalytic　dynamics　and　reaction　intermediates.　Finally,　future　directions　for　Fe　&　horbar;M　DACs　are　proposed,　emphasizing　the　integration　of　advanced　experimental　strategies　with　theoretical　simulations　as　well　as　artificial　intelligence/machine　learning　to　design　highly　active　and　stable　ORR　catalysts,　aiming　to　expand　the　application　of　Fe　&　horbar;M　DACs　in　energy　conversion　and　storage　technologies.