Login | Cas Login
English| 简体中文| 繁体中文

  • Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
成果搜索

Advanced Search

author：

Sun, Hao (Sun, Hao.) [1] | Yuan, Hui (Yuan, Hui.) [2] | Hu, Jiangshan (Hu, Jiangshan.) [3] | Chen, Jiayu (Chen, Jiayu.) [4] | Han, Jie (Han, Jie.) [5] | Wang, Peiyuan (Wang, Peiyuan.) [6] | Lu, Can-Zhong (Lu, Can-Zhong.) [7] | Hu, Ting (Hu, Ting.) [8] | Li, Yuhang (Li, Yuhang.) [9]

Indexed by：

EI

Abstract：

Psoriasis　is　a　prevalent　chronic　inflammatory　disorder　affecting　approximately　0.72%　of　the　Chinese　population.　Currently,　available　treatments　cannot　completely　cure　this　disease.　The　excessive　production　of　reactive　oxygen　species　(ROS)　has　been　considered　to　be　a　key　contributor　to　the　progression　of　psoriasis.　In　this　study,　Ce　and　Mn　were　doped　into　mesoporous　silicon　nanomaterials　with　optimized　ratios　that　could　form　uniform　and　well-dispersed　CM@MSNs　particles,　which　were　able　to　effectively　remove　a　wide　range　of　ROS.　As　a　result,　treatment　with　CM@MSNs　could　reduce　epidermal　hyperplasia　and　prevent　inflammatory　reactions　in　the　imiquimod　(IMQ)-induced　psoriasis-like　model　in　mice.　Mechanistically,　CM@MSNs　might　prevent　the　inflammation　by　repressing　the　IL-17　and　NF-κB　signaling　pathways　and　ameliorating　epidermal　hyperplasia　through　the　activation　of　both　canonical　and　noncanonical　Wnt　signaling　pathways.　In　conclusion,　this　research　could　lead　to　a　promising　treatment　method　for　psoriasis.　This　work　provides　an　example　of　nanoenzymes　for　effectively　scavenging　ROS　of　diseases.　©　2025　American　Chemical　Society.

Keyword：

Mesopores Mesoporous materials Nanocarbon Nanoclay Nanocomposites Nanocrystalline materials Nanodots Nanofibers Reactive oxygen species

Community：

  • [ 1 ] [Sun, Hao]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 2 ] [Sun, Hao]College of Chemistry, Fuzhou University, Fuzhou; 350116, China
  • [ 3 ] [Sun, Hao]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 4 ] [Sun, Hao]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 5 ] [Yuan, Hui]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 6 ] [Yuan, Hui]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 7 ] [Yuan, Hui]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 8 ] [Hu, Jiangshan]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 9 ] [Hu, Jiangshan]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 10 ] [Hu, Jiangshan]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 11 ] [Chen, Jiayu]School of Science and Technology, Hong Kong Metropolitan University, Hong Kong; B0711, Hong Kong
  • [ 12 ] [Han, Jie]School of Science and Technology, Hong Kong Metropolitan University, Hong Kong; B0711, Hong Kong
  • [ 13 ] [Wang, Peiyuan]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 14 ] [Wang, Peiyuan]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 15 ] [Wang, Peiyuan]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 16 ] [Lu, Can-Zhong]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 17 ] [Lu, Can-Zhong]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 18 ] [Lu, Can-Zhong]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 19 ] [Hu, Ting]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 20 ] [Hu, Ting]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 21 ] [Hu, Ting]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 22 ] [Li, Yuhang]State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou; 350002, China
  • [ 23 ] [Li, Yuhang]Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen; 361021, China
  • [ 24 ] [Li, Yuhang]Fujian College, University of Chinese Academy of Sciences, Fuzhou; 350002, China

Reprint 's Address：

Email：

Show more details

Related Keywords：

Related Article：

Source ：

ACS Applied Nano Materials

Year： 2025

Issue： 22

Volume： 8

Page： 11415-11426

5 . 3 0 0

JCR@2023

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count：

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 3

Affiliated Colleges：

Get Fulltext

DOI Library Discovery Baidu Scholar Search Engineering Village
Online/Total：1440/13887633
Address：FZU Library(No.2 Xuyuan Road, Fuzhou, Fujian, PRC Post Code：350116) Contact Us：0591-22865326
Copyright：FZU Library Technical Support：Beijing Aegean Software Co., Ltd. 闽ICP备05005463号-1