Implant-associated　infections　and　inadequate　osseointegration　are　major　contributors　to　orthopedic　implant　failures.　Although　hydrothermally　grown　zinc　oxide　(ZnO)　nanorods　on　titanium　(Ti)　implants　enhance　antibacterial　activity,　their　aggressive　degradation　and　uncontrolled　Zn2+　leaching　do　not　meet　the　requirements　for　bone　implants　and　can　damage　the　surrounding　tissues.　This　study　introduces　a　crystal-damage-free　nanoengineering　mechanism　to　enhance　the　stability　of　ZnO　nanorods　by　utilizing　a　carbon　nanolayer　as　a　sacrificial　template　between　the　ZnO　core　and　TiO2.　This　mechanism　induced　the　formation　of　a　hybrid　Zn2TiO4　heterostructure　within　the　carbon　layer　at　a　low　temperature　of　500　degrees　C　by　reducing　the　required　activation　energy.　This　carbon　layer　acts　as　a　diffusion　barrier,　allowing　the　unilateral　diffusion　of　ZnO　into　TiO2　while　preventing　Ti　diffusion　into　the　ZnO　core.　The　resulting　ZnO@TiO2-6　heterostructure　controlled　Zn2+　leaching　and　exhibited　significant　osteogenic　activity　of　MC3T3-E1　cells　and　potent　antibacterial　efficacy　against　S.　aureus　and　E.　coli　due　to　the　differential　landscape　of　osteoblasts　and　bacteria.　In　vivo　studies　further　confirm　that　ZnO@TiO2-6　heterostructure　eradicated　90%　of　bacteria,　alleviated　inflammation,　and　enhanced　biocompatibility.　Unlike　Ti　implants,　which　lack　antibacterial　properties,　and　ZnO　alone,　which　induces　inflammation,　ZnO@TiO2-6　nanorods　provide　enhanced　stability,　sustained　Zn2+　release,　optimized　ROS　levels,　and　dual　antibacterial　and　osteogenic　functions,　making　them　a　promising　advancement　for　orthopedic　and　dental　implants.