In　advanced　La0.6Sr0.4Co0.4Fe0.6O3-delta　(LSCF)　cathode　for　solid　oxide　fuel　cells,　Sr　segregation　form　a　dense　oxide　layer　that　inhibits　oxygen　reduction　reaction　(ORR)　activity　and　stability.　To　address　this　issue,　this　study　investigates　the　Sr　segregation　in　materials　using　an　optimized　solid-phase　reaction　method.　This　optimized　solid-phase　reaction　method　generated　LSCF　(S-R　LSCF),　introduces　a　homogeneous　microstructure　that　can　effectively　reduce　Sr　migration.　Comparing　sol-gel　generated　LSCF　(S-G　LSCF),　S-R　LSCF　shows　lower　crystallinity,　smaller　particle　size,　and　significantly　less　Sr　segregation.　The　optimized　solid-phase　reaction　is　observed　to　effectively　inhibit　the　segregation　of　Sr　and　improve　the　stability　of　the　material,　which　can　be　attributed　to　the　decreased　formation　of　oxygen　vacancies　raised　by　compressive　stress.　Moreover,　the　thermal　expansion　coefficient　(TEC)　of　S-R　LSCF　is　notably　decreased　to　13.3　x　10-6　K-1,　thereby　substantially　enhancing　the　durability　of　the　material　when　utilized　as　a　cathode.　Such　a　S-R　LSCF　cathode　can　achieve　a　1.42-fold　higher　power　density,　and　a　slower　decay　rate　surpass　6　times　than　that　of　S-G　LSCF.　This　study　effectively　addresses　Sr　segregation　in　LSCF　cathodes,　leading　to　significant　improvements　in　performance　and　stability,　and　provides　a　novel　approach　for　exploring　high-performance　cathode　of　SOFCs.