A　novel　silica-based　monolithic　column　possessing　diethylenetriaminopropyl　ligands　for　hydrophilic　interaction　pressurized　capillary　electrochromatography　is　described.　The　preparation　of　monolithic　stationary　phase　was　based　on　the　individual　silica　matrix　forming　and　subsequent　chemical　bonding.　The　triamino　groups　on　the　surface　of　the　novel　stationary　phase　generated　a　sustainable　anodic　electroosmotic　flow　under　acidic　conditions.　A　variety　of　neutral　and　basic　analytes　were　used　to　evaluate　the　column　performance.　The　monolithic　silica　stationary　phase　exhibited　hydrophilic　interaction　chromatographic　behavior　toward　neutral　solutes.　For　basic　tetracycline　antibiotics,　hydrophilic　interaction　as　well　as　electrophoretic　migration　process　with　the　monoliths　was　observed　and　peak　tailing　was　avoided.