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author:

Li, NB (Li, NB.) [1] | Duan, JP (Duan, JP.) [2] (Scholars:段建平) | Chen, HQ (Chen, HQ.) [3] (Scholars:陈红青) | Chen, GN (Chen, GN.) [4] (Scholars:陈国南)

Indexed by:

SCIE PKU CSCD

Abstract:

A novel flow injection chemiluminescence method has been developed for the determination of doxycycline(DC) based on the inhibition of chemiluminescence reaction of Luminol-KMnO4 by using DC in sodium hydroxide medium. Using different concentrations of KMnO4, a series of good linear regression equations of decreased chemiluminescence intensity and the concentration of DC were obtained with different subsections in the concentration range of 0.005-5.0 mug(.)mL(-1). The detection limit (3sigma) is 2.0 X 10(-3) mug(.)mL(-1). The method has been successfully applied to the determination of DC in a Pharmaceutical preparation.

Keyword:

doxycycline flow injection inhibitory chemiluminescence

Community:

  • [ 1 ] Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 2 ] Fuzhou Univ, Analyt & Testing Ctr, Fuzhou 350002, Peoples R China

Reprint 's Address:

  • 李念兵

    [Li, NB]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China

Email:

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Source :

SPECTROSCOPY AND SPECTRAL ANALYSIS

ISSN: 1000-0593

CN: 11-2200/O4

Year: 2004

Issue: 1

Volume: 24

Page: 15-17

0 . 3 5

JCR@2004

0 . 7 0 0

JCR@2023

ESI Discipline: CHEMISTRY;

JCR Journal Grade:4

Cited Count:

WoS CC Cited Count: 9

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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