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author:

Liu, ES (Liu, ES.) [1] | Dai, ZF (Dai, ZF.) [2] | Huang, JD (Huang, JD.) [3] (Scholars:黄剑东) | Chen, NS (Chen, NS.) [4] | Huang, JL (Huang, JL.) [5] | Huang, ZQ (Huang, ZQ.) [6] | Sun, JC (Sun, JC.) [7]

Indexed by:

Scopus SCIE PKU CSCD

Abstract:

This paper reported the syntheses of amphiphilic substituted metal phthalocyanines containing sulfonic acid groups and phthalimidomethyl groups (MPcSP, M = Zn or Al(OH), S = -SO3-, P = phthalimidomethyl). We have selected zinc phthalocyanine (Zn-D) as the one with better cell killing potential by an in vitro cell survival assay. Over 90% tumor cells were killed with 10 mg/L Zn-D, after they were exposed to 12 J/cm(2) red light.

Keyword:

metal phthalocyanic photodynamic therapy (PDT) photosensitizer syntheses tumor cells

Community:

  • [ 1 ] Fuzhou Univ, Inst Funct Mat, Dept Chem, Fuzhou 350002, Peoples R China
  • [ 2 ] Fujian Med Univ, Canc Pharmacol Res Sect, Fuzhou 350004, Peoples R China

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Source :

ACTA BIOCHIMICA ET BIOPHYSICA SINICA

ISSN: 0582-9879

CN: 31-1940/Q

Year: 1998

Issue: 1

Volume: 30

Page: 31-34

0 . 1 0 6

JCR@1998

3 . 3 0 0

JCR@2023

ESI Discipline: BIOLOGY & BIOCHEMISTRY;

JCR Journal Grade:4

Cited Count:

WoS CC Cited Count: 10

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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