In　order　to　explore　the　feasibility　of　preventing,　delaying　or　curing　prediabetes　by　drinking　vine　tea,　a　mouse　model　of　prediabetes　was　established　by　feeding　a　high-sugar　and　high-fat　diet　and　injection　of　streptozocin　(STZ).　Then　the　model　mice　were　divided　into　model　group,　low-dose　(200　mg/kg　mb)　and　high-dose　(500　mg/kg　mb)　groups　orally　administered　with　total　flavonoid　extract　from　vine　tea,　acarbose　control　group　and　acarbotane-flavonoid　extract　group.Parameters　of　interest　were　detected.　The　results　showed　that　fasting　blood　glucose,　glucose　tolerance,　glycosylated　serum　protein　(GSP)　and　insulin　secretion　levels　in　the　high-dose　treatment　group　were　significantly　lower　than　those　in　the　model　group　(P　©　2019,　China　Food　Publishing　Company.　All　right　reserved.