The　effect　of　the　position　of　the　current-carrying　coil　on　magnetic　field　distribution　was　analyzed　by　using　finite　element　method　for　the　ferrite　core　wound　with　the　current-carrying　coil.　The　magnetic　field　inhomogeneity　function　combined　with　the　finite　element　method　was　then　used　to　optimize　the　magnetic　field　uniformity　for　the　air　gap　of　ferrite　core.　The　optimized　magnetic　field　of　ferrite　core　was　further　applied　to　the　temperature　distribution　analysis　for　magnetic　hyperthermia　by　a　sequential　coupling　method.　The　therapeutic　effect　for　magnetic　hyperthermia　was　evaluated　by　using　the　percentage　of　the　effective　temperature　volume　to　the　tumor　volume　during　treatment　period.　The　results　show　that　the　magnetic　field　for　the　air　gap　with　the　coil　at　both　ends　is　better　than　the　case　at　the　left　end　in　ferrite　core,　which　is　basically　consistent　with　the　analysis　of　equivalent　magnetic　circuit.　In　addition,　the　optimization　method　proposed　in　this　study　can　significantly　improve　the　uniformity　of　the　air-gap　magnetic　field,　can　also　locate　the　maximum　treatment　temperature　to　a　critical　treatment　value　inside　tumor　region,　and　ultimately　improve　the　treatment　effect　for　magnetic　hyperthermia.　©　2023　Central　South　University　of　Technology.　All　rights　reserved.