The　fish　tissues　from　four　species　collected　from　Taihu　Lake,　China,　were　analyzed　including　dorsal,　ventral,　and　tail　muscles,　heart,　liver,　and　kidney.　The　highest　and　lowest　concentrations　of　fatty　acids　were　respectively　observed　in　livers　and　muscles.　There　were　significant　intraspecies　and　interspecies　differences　in　the　compositions　of　most　fatty　acids　among　muscle,　heart,　liver,　and　kidney.　All　the　tissues　were　generally　beneficial　for　consumption　considering　fatty　acids.　People　mainly　consume　the　muscle.　Hence,　the　benefits　from　two　polyunsaturated　fatty　acids,　i.e.,　eicosapentaenoic　acid　(EPA)　and　docosahexaenoic　acid　(DHA),　and　risks　from　PCBs　and　PBDEs　via　fish　consumption　were　evaluated　by　calculating　the　benefit-risk　quotient　(BFQ)　for　the　intake　of　fish　muscle　containing　EPA　+　DHA　vs.　PCBs　or　PBDEs.　The　BFQ　values　considering　carcinogenic　and　noncarcinogenic　effects　for　PCBs　were　similar　to　3000　and　10　times　higher　than　those　of　PBDEs　via　fish　consumption　to　achieve　the　recommended　EPA　+　DHA　intake　of　250　mg　d(-1),　respectively.　The　results　also　suggested　that　the　risk　consuming　the　dorsal　muscle　was　generally　lower　than　the　ventral　and　tail　muscles.　(C)　2012　Elsevier　Ltd.　All　rights　reserved.