A　peroxyoxalate-based　chemiluminescence(CL)　detection　following　capillary　electrophoresis(CE)　separations　for　assaying　amino　acids　is　described.　To　achieve　high　signal　stability　and　sensivity,　a　new　interface　was　designed　including　a　new　mixing　mode　and　a　new　grounding　electrode　mode.　A　platinum　wire-connected　cathode　of　a　high　voltage　source　was　put　onto　a　stainless　steel　needle　tube,　which　was　used　as　grounding　electrode.　The　CE　capillary　was　inserted　into　the　stainless　steel　needle　tube　and　the　capillary　outlet　was　put　on　the　outlet　of　the　needle　tube.　The　CE　capillary　and　two　reagent　capillaries　used　for　delivering　chemiluminescence　reagent　were　fixed　oppositely　to　a　reaction　cell.　Amino　acids　fluorescently　tagged　with　dansyl　chloride　and　naphthalene-2,3-dicarboxaldehyde(NDA)　were　used　for　the　study.　Results　show　this　CE-CL　system　has　good　stability,　resolution,　sensitivity　and　reproducibility.　The　detection　limits　were　1.1　nmol/L　for　dansyl-leucine　(Leu)　and　2.0　nmol/L　for　dansyl-aspartic　acid　(Asp).　The　relative　standard　deviations　of　peak　height　and　migration　time　were　2.3%-3.8%　and　1.2%-1.5%,　respectively.