The　demand　to　recover　value-added　resource　is　intensified　due　to　the　accelerating　growth　of　resource　waste　with　wastewater　discharge.　Here　we　design　pH-responsive　sodium　salts　of　an　imidazole-based　ionic　solid　(im-IS),　im-IS-Na　and　im-IS-2Na,　as　draw　solutes　for　forward　osmosis　(FO)　to　achieve　resource　recovery.　im-IS-Na　and　im-IS-2Na　both　have　an　expanded　structure　and　contain　multiple　ionic　moieties.　These　attributes　make　them　generate　a　sufficient　driving　force　for　FO　separation　and　negligible　solute　losses.　Consequently,　im-IS-Na　and　im-IS-2Na　at　1.0　M　produce　pure　water　fluxes　of　27.5　LMH　and　32.0　LMH,　respectively,　increased　up　to　128　%　relative　to　those　of　conventional　draw　solutes.　im-IS-Na　can　concentrate　the　glycine-containing　solution　efficiently　with　a　water　flux　of　17.6　LMH,　183　%　and　25　%　higher　than　those　of　NaCl　and　NH4HCO3,　separately.　Particularly,　im-IS-Na　preserves　the　glycine　product　intact,　whereas　NaCl　and　NH4HCO3　either　denature　or　contaminate　it　resulting　from　their　severe　reverse　diffusion.　im-IS-Na　and　im-IS-2Na　are　conveniently　regenerated　by　pH　regulation　involving　no　organic　solvent　and　external　pressure　which　are　commonly　used　in　recycling　other　draw　solutes.　im-IS-Na　and　im-IS-2Na　thus　demonstrate　their　superiority　as　FO　draw　solutes　to　recover　value-added　resources.　©　2024　Elsevier　B.V.